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An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamine or ethylamine, or ...
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide -based reagents used as accelerators for vulcanization. It is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators ). The amine itself is an effective corrosion inhibitor.
Eticyclidine ( PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, [2] but research into PCE was not continued after the development of ...
mechanism. In organic chemistry, the Ei mechanism ( Elimination Internal/Intramolecular ), also known as a thermal syn elimination or a pericyclic syn elimination, is a special type of elimination reaction in which two vicinal (adjacent) substituents on an alkane framework leave simultaneously via a cyclic transition state to form an alkene in ...
A much more convenient method for the synthesis of β-phenethylamine is the reduction of ω-nitrostyrene by lithium aluminium hydride in ether, whose successful execution was first reported by R. F. Nystrom and W. G. Brown in 1948. Phenethylamine can also be produced via the cathodic reduction of benzyl cyanide in a divided cell.
Dicyclohexylamine. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Dicyclohexylamine is a secondary amine with the chemical formula HN (C 6 H 11) 2. It is a colorless liquid, although commercial samples can appear yellow. It has a fishy odor, typical for amines.
Chemical synthesis. In chemistry, chemical synthesis ( chemical combination) is the artificial execution of chemical reactions to obtain one or several products. [1] This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable.
Retrosynthetic analysis. Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents. Each precursor material is examined using the same method.