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Trisomy 21. Down syndrome (also known by the karyotype 47,XX,+21 for females and 47,XY,+21 for males) [98] is mostly caused by a failure of the 21st chromosome to separate during egg or sperm development, known as nondisjunction. [91] As a result, a sperm or egg cell is produced with an extra copy of chromosome 21; this cell thus has 24 ...
ML. Internet TLD. .ml. Mali, [ c ] officially the Republic of Mali, [ d ] is a landlocked country in West Africa. It is the eighth-largest country in Africa, with an area of over 1,241,238 square kilometres (479,245 sq mi). [ 9 ] The country is bordered to the north by Algeria, to the east by Niger, to the northwest by Mauritania, to the south ...