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Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
Highly lipophilic beta blockers include penbutolol, pindolol, propranolol, and timolol, moderately lipophilic beta blockers include acebutolol, betaxolol, bisoprolol, carvedilol, metoprolol, and nebivolol, and low lipophilicity or hydrophilic beta blockers include atenolol, carteolol, esmolol, labetalol, nadolol, and sotalol.
The progress in β-blocker development led to the introduction of drugs with variety of properties. β-blockers were developed having a relative selectivity for cardiac β1-receptors (for example metoprolol and atenolol), partial adrenergic agonist activity , concomitant α-adrenergic blocking activity (for example labetalol and carvedilol) and ...
Beta-blockers Atenolol; Bisoprolol; Carvedilol; Esmolol; Metoprolol; Nebivolol; Propranolol; Timolol; Beta blocker Propranolol also has some sodium channel-blocking effect. Decrease mortality in patients with myocardial infarction; Prevent recurrence of tachycardia; III Potassium channel blockers Amiodarone; Dofetilide; Dronedarone; E-4031 ...
The combination of beta blockers and antihypertensive drugs will work on different mechanism to lower blood pressure. For example, the co-administration of beta-1 blocker atenolol and ACE inhibitor lisinopril could produce a 50% larger reduction in blood pressure than using either drug alone. Hypertensive drugs
C07E Beta blocking agents and vasodilators C07EA Beta blocking agents, non-selective, and vasodilators C07EB Beta blocking agents, selective, and vasodilators C07F Beta blocking agents, other combinations C07FB Beta blocking agents and calcium channel blockers C07FB02 Metoprolol and felodipine C07FB03 Atenolol and nifedipine
It is a non-selective beta blocker and works by blocking β1-adrenergic receptors in the heart and β2-adrenergic receptors in blood vessels. Nadolol was patented in 1970 and came into medical use in 1978. It is available as a generic medication.
It is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was patented in 1962 and approved for medical use in 1964. It is on the World Health Organization's List of Essential Medicines. Propranolol is available as a generic medication.
Nebivolol is a beta blocker used to treat high blood pressure and heart failure. As with other β-blockers, it is generally a less preferred treatment for high blood pressure. It may be used by itself or with other blood pressure medication. It is taken by mouth. Common side effects include dizziness, feeling tired, nausea, and headaches.
Template:Beta blockers. Beta-2 adrenergic antagonist. Beta-3 adrenergic antagonist. Betaxolol. Bevantolol. Bimatoprost/timolol. Bisoprolol. Bopindolol. Bornaprolol.