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M22 →. The M21 bus route constitutes a public transit line in Manhattan, New York City. The M21 operates between the West Village and the Lower East Side, serving as a Houston Street crosstown. The M9 and M21 are operated by the New York City Transit Authority, and based out of the Michael J. Quill Depot.
The fleet consists of over 5,700 buses of various types and models for fixed-route service, making MTA RBO's fleet the largest public bus fleet in the United States. The MTA also has over 2,000 vans and cabs for ADA paratransit service, providing service in New York City, southwestern Nassau County, and the city of Yonkers.