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A generic version of dapagliflozin was approved by the US FDA in February 2022, but cannot be sold until October 2025. A generic version was approved in Canada in May 2023.
Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and works by increasing sugar loss in urine. [2] Empagliflozin was approved for medical use in the United States and in the European Union in 2014. [11] [22] [23] It is on the World Health Organization's List of Essential Medicines. [24]
At a dose of 2 mg per day of rilmenidine, controlled comparative studies versus clonidine (0.15 to 0.30 mg/day) or alpha-methyldopa (500 to 1000 mg/day) demonstrated that the incidence of side effects was significantly lower with rilmenidine than with either clonidine or a-methyldopa.
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. [8] It is used either by mouth or injection into a muscle. [8]
Lisdexamfetamine, sold under the brand names Vyvanse and Elvanse among others, is a stimulant medication that is used to treat attention deficit hyperactivity disorder (ADHD) in children and adults and for moderate-to-severe binge eating disorder in adults. [15] Lisdexamfetamine is taken by mouth.
Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion. [5] It works by inactivating (H+/K+)-ATPase function in the stomach. [9] [5] Study of pantoprazole began in 1985, and it came into medical use in Germany in 1994. [10] It is available as a generic medication.
Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] Escitalopram is mainly used to treat major depressive disorder and generalized anxiety disorder. [7] It is taken by mouth, [7] available commercially as an oxalate salt exclusively.
Linagliptin, sold under the brand name Tradjenta among others, is a medication used to treat type 2 diabetes (but not type 1) in conjunction with exercise and diet. [8] [9] It is generally less preferred than metformin and sulfonylureas as an initial treatment. [8] [10] It is taken by mouth. [8]
Ranolazine, sold under the brand name Ranexa among others, is a medication used to treat heart related chest pain. [5] Typically it is used together with other medications when those are insufficient. [5] [6] Therapeutic benefits appear smaller in females than males. [5] It is taken by mouth.
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus.
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