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The Games Maker (Spanish: El inventor de juegos) is a 2014 Argentine-Canadian family adventure film co-written and directed by Juan Pablo Buscarini and starring David Mazouz, Joseph Fiennes, Megan Charpentier, Tom Cavanagh and Ed Asner.
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The adenylate energy charge is an index used to measure the energy status of biological cells.. ATP or Mg-ATP is the principal molecule for storing and transferring energy in the cell : it is used for biosynthetic pathways, maintenance of transmembrane gradients, movement, cell division, etc...
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [3] [4] Improper ADP-ribosylation has been implicated in some forms of cancer. [5]
ADP-ribose polymers, either free or PARP1 bound, are able to inhibit DNA methyltransferase activity at CpG sites. [20] Thus, CTCF is involved in the cross-talk between poly(ADP-ribosyl)ation and DNA methylation, an important epigenetic regulatory factor. [19]
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